In the game, the heroine dies, but this does not mean that the character has disappeared forever — in the Resident Evil series, heroes have already appeared after death.
In an interview with TheGamer, Maggie Robertson, who played Dimitrescu, said that she is ready to return if Capcom offers.
Do I want to return to her? Of course, the answer to that will always be "yes." Do I have any idea about Capcom's plans for her? Absolutely not. I'm just an actress. I'll find out about it at the same time as you.
Dimitrescu partially returned in Resident Evil Requiem — in the game, Deluxe Edition owners can try on her image on the heroine Grace Ashcroft. Capcom clearly knows about the character's popularity, so her return in the future cannot be ruled out.