In an interview, the game's producer, Masato Kumazawa, stated that Resident Evil Requiem is comparable in length to Resident Evil 4 Remake. This refers to a full-fledged story campaign without the feeling of a premature ending.
Completing the main story will take approximately 16–19 hours. Capcom has also confirmed the ability to switch the camera between first-person and third-person views. This changes the perception of exploration, combat, and horror elements, which may lead some players to replay the game to see what's happening from a different perspective.
The developers have also confirmed the presence of chapters. Resident Evil Requiem is divided into a number of episodes comparable to Resident Evil 4 Remake, indicating a similar campaign structure.